genetics eco

Nexalife

Pharmaceuticals
biotech Therapeutic Areas

Oncology

Targeting cancer at the molecular level.

Our oncology pipeline is focused on the discovery and development of next-generation therapies that harness the immune system and target tumor-specific vulnerabilities.

Our Approach

Precision Medicine for Solid Tumors

We are pioneering a multi-modal approach to treating cancer. By identifying specific genetic mutations and protein expressions within tumor cells, we design targeted small molecules and antibody-drug conjugates (ADCs) that strike with precision, minimizing damage to healthy tissue.

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    Immuno-Oncology

    Reactivating the body's natural defense systems to recognize and destroy cancer cells.

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    Tumor Microenvironment

    Modulating the surrounding cellular environment to prevent tumor growth and metastasis.

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    Synthetic Lethality

    Exploiting specific genetic defects in cancer cells to induce cell death.

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Mechanism of Action: NX-202

Key Drug Targets

Our research engine is focused on high-value targets with the potential to transform standard of care.

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coronavirus
Phase 3

NX-202 (Anti-PD-L1)

A novel checkpoint inhibitor designed to have higher affinity and reduced immune-related adverse events.

Solid Tumors

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Phase 2

NX-550 (KRAS G12C)

Targeting the "undruggable" KRAS mutation with a highly selective small molecule inhibitor.

NSCLC / Colorectal

science
Preclinical

NX-800 (ADC Platform)

Next-generation Antibody-Drug Conjugate utilizing a cleavable linker for targeted delivery of potent payloads.

Breast / Ovarian

Active Clinical Trials

NEX-ONC-301 Recruiting

Phase 3 Study of NX-202 in Advanced Non-Small Cell Lung Cancer

location_on 45 Sites
group 600 Patients
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NEX-ONC-205 Recruiting

Phase 2 Basket Trial of NX-550 in Solid Tumors with KRAS G12C Mutation

location_on 22 Sites
group 120 Patients
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NEX-ONC-102 Active, Not Recruiting

Phase 1/2 Dose Escalation of NX-800 in Refractory Ovarian Cancer

location_on 8 Sites
group 45 Patients
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Partner with our Oncology Team

We are actively seeking collaborations to accelerate the development of transformative cancer therapies.